G4X Performance
Robust performance across tissue types and applications.
Sensitive Transcript Detection
G4X employs padlock probes and rolling circle amplification to achieve high sensitivity in transcript detection. This allows for the accurate identification and localization of even low-abundance transcripts within a tissue sample.
Low False Discovery Rates
Padlock probes with dual-binding sites to ensure high specificity in transcript detection. Furthermore, the platform incorporates robust internal controls to minimize variability and ensure accurate quantification of target transcripts within each experiment.
Exceptional Reproducibility
Robust chemistry, precisely controlled workflow, and inherent system throughput enable exceptional section-to-section reproducibility within a lane, across flow cells and across runs. This consistency ensures reliable and comparable results across multiple experiments and samples, facilitating robust spatial mulitiomic analysis
Correlative Multiomic Results
Simultaneous identification of protein and transcript expression enables internal validation of single-cell results, strengthening confidence in results and revealing the complex interplay between gene expression and protein activity.
Precise Single Cell Insights
Combined, multiomic analysis with G4X provides a detailed understanding of cellular identity and function within the tissue microenvironment for a deeper understanding of cell interactions and neighborhood dynamics.
Comprehensive 3D Spatial Analysis
Exceptional reproducibility of multiomic results on G4X enables robust serial section reconstruction, for a complete 3D understanding of the tissue microenvironment with enhanced insights into cellular organization, interactions, and function.
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